CBD and THC kills cancer cells
In each cell, there are some factors of so-called ‘fatty acids interconvertible-sphingo’, which controls the cell’s life and death. These factors are called ‘sphingo-fatty acid Rheostat’ (SR). If the internal ceramide (a chemical of this) is high, so is cell death (apoptosis) safe while cell activity is high at low levels of ceramide.
When THC connects to the CB1 or CB2 receptors in the cancer cell, it causes an increase in ceramide synthesis that controls against cell death. A normal, healthy cell does not produce ceramide, if the THC is present, and is therefore not affected by the cannabinoid.
The cancer cells die – not because of cell poison – but because a small shift in the cells mitochondria. Mitochondrias are cell’s ‘power center’.
In most cells, there is a cell nucleus and mitochondria, as well as several other organelles in the cell.
Mitochondria are to produce energy (ATP) to the cell. As ceramide is increased, thereby increasing SR, at the same time increases the mitochondrial permeability of cytochrome, which is an important protein in energy syntheses. Cytochrome C is pushed out of the mitochondria and thereby killing the energy supply to the cell.
Ceramide also causes a re-toxic stress of the cancer cell nucleus; thereby producing a protein called p53, whose job it is to disturb the calcium metabolism in the mitochondria. As if that was not enough, so disturbs ceramide the cell’s digestive system, which produces nutrients to all cell functions. Ceramide and other sphingo fatty acids, inhibits actively possible pathways for cell survival and causes cancer cell death.
The key to this process is the accumulation of ceramide in the system, which means that when one takes a period of therapeutic amounts of CBD and THC, one maintains a metabolic pressure to cancer cell death.
How can it be that the body can take a simple plant enzyme and use it for true healing in many different physiological systems?
This inner cannabinoid system exists in all ‘animal’ living where just waiting to be activated via its external cannabinoid match. Interestingly covers our own inner cannabinoid system, all cells and nerves. It is a ‘messenger’ of information that flows between our immune system and the central nervous system (CNS). It is responsible for the protection of the nervous system and ‘fixes’ the immune system at the micro level. This is the primary control system that maintains equilibrium – our well-being.
How gets the job done at the cellular level, and how the body produces cannabinoids?
What we see here is that the inner cannabinoids derived from nerve cells right at the synapse – the nerve end or staging. When the body is affected by example, illness or injury, it calls immediately the internal cannabinoid system and directs the immune system to heal. If these equilibrium sustaining systems weakens, is it logic that external cannabinoids can heal and soothe. They help the body in the most natural way.
To see how it works, we imagine cannabinoids as a three-dimensional molecule; one part fits the nerve and immune cell receptors like a key in a lock. There are at least two kinds of receptors CB1 (CNS) and CB2 (immune system). Generally activates CB1 the central nervous system (CNS) and CB2 activates the immune system – but it’s more complex than that. Both THC and anandamide activates both receptors. Other cannabinoids activates a second receptor. Among the strings of Cannabis, pulling Cannabis Sativa against the CB1 receptor, while Cannabis indica draw against CB2. Therefore, Sativa more nerve active while Indica are more immune active. Sativa dominated addition of THC cannabinoids while Indica primarily dominated by CBD.
It is well known that THC and CBD can be replaced / mimes of anandamide in the body. Therefore activate the mimic outer cannabinoid by stress, injuries or disease in which the body requires more internal anandamide. If the stress is of short duration, the treatment can be short-lived. If the need are persistent like cancer disease there is need for treatment to exert unrelenting pressure on the sustaining part of equilibrium systems.
Interestingly, it has been found that the cannabinoids THC and CBD have the ability to directly kill cancer cells without prior ‘balances’ in the immune system. THC and CBD ‘steals’ shortcut to directly inhibit tumour growth.
As an aside, it has been discovered that CBD inhibits the reuptake of anandamide in the cells. Here we see that cannabidiol (CBD) helps the body to maintain its natural inner cannabinoids by inhibiting the enzyme that breaks down anandamide.